Our work place has undergone a change from mostly PDF job flows to mostly PostScript. When we were PDF we did a lot of spot color matching and such and now I am being tasked to make sections of color in the postscript job flow.
Other than using a blanket approach by custom output profiles I am at a loss.

Is there a RGB Input or CMYK input source that I could or should be using?

I have been reading a number of articles from the web that allude to several things:
1) Correct settings in the creation of the file to begin with
2) Correct settings when using Distiller
3) Having a PS receptive commercial profile for output
Most of these articles are older than 2010 so may be out of date but I wanted to ask.

I am managing Konica MInolta C1100s, using CWS, Fiery CS IC-310H PS Color Server2.1us, FS150 Pro.